Photoinduced formation of beta-oxy-alpha,alpha-disubstituted-alpha-amino acid derivatives from ketoximes.

ABSTRACT

[reaction see text] The first intermolecular radical addition onto ketoxime ethers is described. beta-Oxygenated quaternary alpha-amino acid derivatives IotaIota were obtained upon irradiation of alpha-alkoxycarbonyl ketoxime ethers Iota in the presence of suitable alpha-alkoxy carbon radical precursors and a sensitizer.