Management strategies for pyoderma gangrenosum: case studies and review of literature.
Ann Plast Surg
; 47(3): 310-5, 2001 Sep.
Article
em En
| MEDLINE
| ID: mdl-11562037
ABSTRACT
Pyoderma gangrenosum (PG) is a systemic disease with cutaneous manifestations consisting of necrotizing ulceration. The etiology of PG is controversial, and optimal management strategies have not been established. Current management is primarily medical to control the systemic inflammatory process, with occasional surgical intervention at the ulcer site. Based on the current literature and on the authors' clinical experience, the optimal outcome depends on early diagnoses and a combination of medical and surgical therapy. Initial management is directed toward medical control of the inflammatory process and local wound care. Surgical strategies involve recipient site preparation via local wound care and serial allograft followed by autologous skin graft or muscle flap coverage when necessary. Long-term wound stabilization is obtained only through control of the systemic and local inflammatory process.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Retalhos Cirúrgicos
/
Prednisona
/
Transplante de Pele
/
Pioderma Gangrenoso
/
Anti-Inflamatórios
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article