Two cases of non-O157:H7 Escherichia coli hemolytic uremic syndrome caused by urinary tract infection.
Am J Kidney Dis
; 38(4): E22, 2001 Oct.
Article
em En
| MEDLINE
| ID: mdl-11576909
ABSTRACT
Escherichia coli serotype O157H7 is a leading cause of diarrhea and hemolytic uremic syndrome (HUS). Because of the limitations of current diagnostic techniques, the prevalence of non-O157H7 Shiga toxin-producing E coli strains is not known. We describe two patients with HUS in whom no E coli O157H7 was demonstrable in stool cultures. On culture of the urine, the first patient was found to have E coli O113H21 strain, and the second patient had E coli O6H1 serotype. Shiga toxin production (stx2) by the O113H21 isolate was confirmed. The first patient required 15 days of peritoneal dialysis and subsequently recovered renal function. At last follow-up, serum creatinine was 0.9 mg/dL. The second patient had preservation of renal function throughout the acute illness with serum creatinine of 0.5 mg/dL. The clinical presentation, bacteriology, course, and outcome as well as epidemiologic implications of the increasing number of patients with E coli urinary tract infections associated with HUS are discussed. These cases illustrate the need to investigate patients with nondiarrheal HUS for infection with Shiga toxin-producing E coli of the non-O157 strain variety.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Infecções por Escherichia coli
/
Síndrome Hemolítico-Urêmica
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article