Pemphigus foliaceus developing after metastasis of cutaneous squamous cell carcinoma to regional lymph nodes.

Inaoki, M; Kaji, K; Furuse, S; Fujimoto, A; Komatsu, N; Takata, M; Takehara, K

Inaoki, M; Kaji, K; Furuse, S; Fujimoto, A; Komatsu, N; Takata, M; Takehara, K.

Afiliação

Inaoki M; Department of Dermatology, Kanazawa University School of Medicine, 13-1, Takaramachi, Kanazawa, Ishikawa 920-8641, Japan. inaoki-m@med.kanazawa-u.ac.jp

J Am Acad Dermatol ; 45(5): 767-70, 2001 Nov.

Article em En | MEDLINE | ID: mdl-11606932

ABSTRACT

ABSTRACT

We describe a patient in whom pemphigus foliaceus developed after cutaneous squamous cell carcinoma (SCC) metastasized to regional lymph nodes. Immunologic analysis revealed that production of anti-desmoglein 1 autoantibodies started when SCC metastasized, and the SCC expressed desmoglein 1, suggesting a pathogenic role of metastasized SCC in developing pemphigus foliaceus.

Assuntos

Caderinas/análise; Carcinoma de Células Escamosas/secundário; Metástase Linfática; Pênfigo/etiologia; Neoplasias Cutâneas/patologia; Idoso; Autoanticorpos/análise; Caderinas/biossíntese; Desmogleína 1; Feminino; Humanos; Pênfigo/patologia

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Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma de Células Escamosas / Caderinas / Pênfigo / Metástase Linfática Idioma: En Ano de publicação: 2001 Tipo de documento: Article

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