Effects of acute decrease in systemic afterload on accuracy of Doppler-derived left ventricular rate of pressure rise measurement in anesthetized patients.
J Am Soc Echocardiogr
; 14(12): 1161-5, 2001 Dec.
Article
em En
| MEDLINE
| ID: mdl-11734782
ABSTRACT
OBJECTIVES:
This study was designed to describe exactly the effects of acute decrease in systemic afterload on the accuracy of Doppler-derived left ventricular rate of pressure rise (LV DeltaP/Delta(t)) measurements compared with other routinely used indices of systolic function.METHODS:
Twelve patients scheduled for coronary artery bypass grafting were studied. After induction of anesthesia (T0), afterload was modified by incremental administrations of nicardipine (T1-4). At each step of the procedure, thermodilution-derived cardiac index, left ventricular (LV) fractional area change, and LV DeltaP/Delta(t) were measured, and systemic vascular resistances were calculated.RESULTS:
During the procedure, the systemic vascular resistances decrease averaged 13.4%. Systemic vascular resistances were correlated with LV DeltaP/Delta(t) (r = 0.843, P =.003) but inversely correlated with cardiac index (r = -0.782, P =.005) and LV fractional area change (r = -0.887, P =.003).CONCLUSION:
In conclusion, and inversely to cardiac index or LV fractional area change, LV DeltaP/Delta(t) does not overestimate LV contractility in the presence of an acute decrease in systemic afterload.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Sístole
/
Função Ventricular Esquerda
/
Pressão Ventricular
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article