Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.
Ann Intern Med
; 135(12): 1019-28, 2001 Dec 18.
Article
em En
| MEDLINE
| ID: mdl-11747380
ABSTRACT
BACKGROUND:
Initial findings from the Dietary Approaches to Stop Hypertension (DASH)-Sodium Trial demonstrated that reduction of sodium intake in two different diets decreased blood pressure in participants with and without hypertension.OBJECTIVE:
To determine effects on blood pressure of reduced sodium intake and the DASH diet in additional subgroups.DESIGN:
Randomized feeding study.SETTING:
Four clinical centers and a coordinating center.PARTICIPANTS:
412 adults with untreated systolic blood pressure of 120 to 160 mm Hg and diastolic blood pressure of 80 to 95 mm Hg. INTERVENTION Participants followed the DASH diet or a control (typical U.S.) diet for three consecutive 30-day feeding periods, during which sodium intake (50, 100, and 150 mmol/d at 2100 kcal) varied according to a randomly assigned sequence. Body weight was maintained. MEASUREMENTS Systolic and diastolic blood pressure.RESULTS:
In all subgroups, the DASH diet and reduced sodium intake were each associated with significant decreases in blood pressure; these two factors combined produced the greatest reductions. Among nonhypertensive participants who received the control diet, lower (vs. higher) sodium intake decreased blood pressure by 7.0/3.8 mm Hg in those older than 45 years of age (P < 0.001) and by 3.7/1.5 mm Hg in those 45 years of age or younger (P < 0.05).CONCLUSION:
The DASH diet plus reduced sodium intake is recommended to control blood pressure in diverse subgroups.
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Base de dados:
MEDLINE
Assunto principal:
Pressão Sanguínea
/
Dieta Hipossódica
/
Hipertensão
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article