Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2.
Oncogene
; 20(57): 8203-14, 2001 Dec 13.
Article
em En
| MEDLINE
| ID: mdl-11781836
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Ativação Transcricional
/
Receptor IGF Tipo 1
/
Estabilidade de RNA
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article