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Meiosis activating sterols derived from diosgenin.
Murray, Anthony; Grøndahl, Christian; Ottesen, Jan L; Faarup, Peter.
Afiliação
  • Murray A; Novo Nordisk A/S, Novo Nordisk Park, 2760, Maløv, Denmark. amur@novodisk.com
Bioorg Med Chem Lett ; 12(4): 715-7, 2002 Feb 25.
Article em En | MEDLINE | ID: mdl-11844708
ABSTRACT
Continuing research based on the meiosis activation properties of the endogenous sterol FF-MAS is reported. The synthesis and SAR of 16- and 26-substituted sterols are described, utilising diosgenin as starting material. Selected sterols were tested for their ability to induce oocyte maturation in hypoxanthine arrested mouse oocytes in vitro.
Assuntos
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Base de dados: MEDLINE Assunto principal: Esteróis / Diosgenina / Meiose Idioma: En Ano de publicação: 2002 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Esteróis / Diosgenina / Meiose Idioma: En Ano de publicação: 2002 Tipo de documento: Article