[Diagnostic significance of albumin transporting characteristics and blood level of troponin T in myocardial infarction]. / Diagnosticheskoe znachenie transportnykh svoistv al'bumina i soderzhaniia v krovi troponina T pri infarkte miokarda.
Klin Lab Diagn
; (1): 3-7, 2002 Jan.
Article
em Ru
| MEDLINE
| ID: mdl-11855337
ABSTRACT
Serum albumin binding capacity (ABC) was studied using K-35 hydrophobic fluorescent probe in order evaluate the passive transfer and absorption of saturated fatty acids (s-FA) by the cells. ABC decreases on day 3 of myocardial infarction and remains low till discharge and is paralleled by hyperTG. We believe that ABC decrease reflects activation of passive transfer and absorption of s-FA by the cells during simultaneous blocking (presumably by acute phase proteins) of active apoE/B-100 receptor endocytosis of s-FA in the form of TG as VLDL remnants. Decrease of ABC reflects a later than erythrocyte sedimentation rate and acute phase proteins normalization of metabolic consequences of inflammation. ABC helps indirectly evaluate the blocking of active (receptor) absorption of s-FA in the form of TG and activation of passive absorption of s-FA from associations with albumin by the cells.
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Base de dados:
MEDLINE
Assunto principal:
Albumina Sérica
/
Troponina T
/
Infarto do Miocárdio
Idioma:
Ru
Ano de publicação:
2002
Tipo de documento:
Article