Extended repertoire of genes encoding variable surface lipoproteins in Mycoplasma bovis strains.
Infect Immun
; 70(4): 2220-5, 2002 Apr.
Article
em En
| MEDLINE
| ID: mdl-11895991
ABSTRACT
A genomic cluster of vsp genes was previously shown to mediate high-frequency phenotypic switching of surface lipoprotein antigens in the bovine pathogen Mycoplasma bovis. This study revealed that field strains of M. bovis possess modified versions of the vsp gene complex in which extensive sequence variations occur primarily in the reiterated coding sequences of the vsp structural genes. These findings demonstrate that there is a vastly expanded potential for antigenic variation within populations of this organism.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas da Membrana Bacteriana Externa
/
Lipoproteínas
/
Mycoplasma
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article