[Lower limb occlusive arteriopathy: retrospective analysis of 73 patients with onset before the age of 50 years]. / Les artériopathies des membres inférieurs débutant avant 50 ans.
J Mal Vasc
; 27(2): 69-76, 2002 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-12015483
ABSTRACT
OBJECTIVES:
Juvenile peripheral obstructive arterial diseases (POAD) have been poorly investigated but account for 1 to 7% of POAD. We analyzed retrospectively a cohort of patients with onset before the age of 50 years. PATIENTS ANDMETHODS:
Seventy-three patients (60 males and 13 females) were divided into 4 groups (Buerger's disease TAO, atheromatous PAOD, auto-immune POAD, arteriopathy of undetermined origin).RESULTS:
The first symptoms occurred at 38 +/- 8 years of age. Fourteen patients (20%) had TAO, 51 (70%) atheromatous POAD, 4 (5%) POAD with systemic or autoimmune disease, and 4 (5%) undetermined POAD. Age of onset was earlier in TAO (35 +/- 8 vs 40 +/- 8 years, p=0.046), smoking greater in the atheroma group (33 +/- 16 vs 24 +/- 14 pack-years, p=0.033). Fifty-three POAD patients had dyslipidaemia and 26% hypertension. Regular cannabis intake was more frequent in the TAO group (21 vs 8%). At the time of medical care, Fontaine's stage was more frequently stage II in atheroma patients (57 vs 14%) and stage IV in TAO patients (86 vs 35%). TAO was diagnosed in 43% cannabis users and in 19% non users.CONCLUSION:
The main etiology of juvenile POAD is atheroma, followed by TAO. Cannabis users account for at least 10% of these patients. They are characterized by lower tobacco intake, more distal lesions, more frequent involvement of the upper limbs. They present more frequently as TAO.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Arteriopatias Oclusivas
/
Arteriosclerose
/
Doenças Autoimunes
/
Tromboangiite Obliterante
/
Doenças Vasculares Periféricas
Idioma:
Fr
Ano de publicação:
2002
Tipo de documento:
Article