Review of current research projects under way in Australia related to laryngeal cancer.

ABSTRACT

Research in laryngeal cancer in Australia has been largely confined to the study of serial sections of tumor specimens to determine the methods of spread of carcinoma. More recently, a prospective trial, using BCG and Methotrexate in terminal epidermoid carcinoma patients. It is strongly urged that research be directed towards international data collection and double blind prospective clinical trials of modes of therapy for comparable lesions. It is also felt that more basic research should be directed towards determining the role of smoking in the pathogenesis of laryngeal cancer, and the mechanism of action of immunotherapy and chemotherapy.