Effects of cisapride on colonic transit in patients with progressive systemic sclerosis.
Clin Rheumatol
; 21(4): 271-4, 2002 Aug.
Article
em En
| MEDLINE
| ID: mdl-12189451
ABSTRACT
Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.
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Base de dados:
MEDLINE
Assunto principal:
Escleroderma Sistêmico
/
Fármacos Gastrointestinais
/
Trânsito Gastrointestinal
/
Constipação Intestinal
/
Cisaprida
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article