Microwave exposure induces Hsp70 and confers protection against hypoxia in chick embryos.
J Cell Biochem
; 86(3): 490-6, 2002.
Article
em En
| MEDLINE
| ID: mdl-12210755
ABSTRACT
To determine if microwave exposure could elicit a biological effect in the absence of thermal stress, studies were designed in which chick embryos were exposed to athermal microwave radiation (915 MHz) to look for induction of Hsp70, a protein produced during times of cellular stress that aids in the protection of cellular components. Levels of Hsp70 were found to increase within 2 h, with maximum expression ( approximately 30% higher than controls) typically occurring by 3 h from the start of exposure. Other embryos were exposed to microwave radiation prior to being subjected to hypoxic stress, and were found to have significantly higher survival (P < 0.05) following re-oxygenation than non-exposed controls. The results of these studies indicate that not only can athermal microwave exposures activate the stress protein response pathway; they can also enhance survivability following exposure to a subsequent, potentially lethal stress. From a public health standpoint, it is important that more studies be performed to determine if repeated exposures, a condition likely to be found in cell phone use, are still beneficial.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas de Choque Térmico HSP70
/
Hipóxia
/
Micro-Ondas
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article