[Cytoplasmic estradiol and progesterone receptors in human endometrium with normal menstrual cycles: 116 cases].

PIP: Endomentrial samples were obtained from 116 patients who underwent hysterectomy or dilatation and currettage. The normal menstrual cycles were determined on the basis of clinical and histological features. They were divided into 6 categories: early, middle and late proliferative and secretory phases. The highest progesterone receptor level was present in the late profilerative phase and the lowest in the late secretory phase. Expect for the fact that the lowest level of estrogen receptor was present in the late secretory phase, differences in the other phases were not significant. The data was split into younger and older groups and analyzed separately. In the proliferative phase, the estrogen and progesterone receptor levels were higher in the perimenopausal group than in the premenopausal group, but no significant differences were found in the secretory phase. On the whole, the estrogen and progesterone receptor levels were higher in proliferative than in the secretory samples, and the progesterone receptor level was much higher than the estrogen receptor level in both phases. These findings were in agreement with data from the literature. Simultaneously, the estradiol and progesterone levels in serum and cytosol were measured in some cases. The progesterone receptor level was closely correlated with progesterone level in serum and tissues (negative correlation) and also closely correlated with estradiol in tissues (positive correlation). The variations in the estrogen and progesterone receptors in endometrial cytosol during the normal menstrual cycle of Chinese women may offer some useful information for further basic or clinical research in the fields of planned parenthood and gynecology. (author's modified)^ieng