[Combined treatment for locally advanced carcinoma of uterine cervix].
Zhonghua Zhong Liu Za Zhi
; 24(5): 508-10, 2002 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-12485512
ABSTRACT
OBJECTIVE:
To evaluate the feasibility of surgical management for patients with locally advanced carcinomas of uterine cervix after radical radiation therapy who were prone to develop central recurrence.METHODS:
These 40 patients were treated by combined pre-operative radiotherapy with dose at point A of > 70 Gy in 30 patients, 60 approximately 70 Gy in 7, 50 approximately 59 Gy in 2 and 44 Gy in 1. The interval between radiation and surgery was 1 - 6 weeks. Extrafascial hysterectomy was performed in 15 patients, subradical hysterectomy in 23 and radical hysterectomy with pelvic lymphadenectomy in 2 cases.RESULTS:
These patients have been followed up for 1 - 8 years with 2 died of other diseases and 12 died of cancer. Eighteen of the 26 survivors have been followed up for more than 5 years. The 3- and 5-year survival rates were 74.9% and 66.8%. Half of the death occurred within the first year after treatment. The 2-year death rate was 9/12 (75.0%). Three patients suffered from long term complications after the treatment, but all were cured by conservative management.CONCLUSION:
The combination of hysterectomy performed shortly after radical radiotherapy, ie, for patients with locally poor prognostic cervical carcinoma is reasonable and feasible.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo do Útero
Idioma:
Zh
Ano de publicação:
2002
Tipo de documento:
Article