Human immunodeficiency virus reverse transcriptase and protease sequence database.
Nucleic Acids Res
; 31(1): 298-303, 2003 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-12520007
ABSTRACT
The HIV reverse transcriptase and protease sequence database is an on-line relational database that catalogues evolutionary and drug-related sequence variation in the human immunodeficiency virus (HIV) reverse transcriptase (RT) and protease enzymes, the molecular targets of antiretroviral therapy (http//hivdb.stanford.edu). The database contains a compilation of nearly all published HIV RT and protease sequences, including submissions to GenBank, sequences published in journal articles and sequences of HIV isolates from persons participating in clinical trials. Sequences are linked to data about the source of the sequence, the antiretroviral drug treatment history of the person from whom the sequence was obtained and the results of in vitro drug susceptibility testing. Sequence data on two new molecular targets of HIV drug therapy--gp41 (cell fusion) and integrase--will be added to the database in 2003.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Protease de HIV
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HIV-1
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Bases de Dados de Proteínas
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Transcriptase Reversa do HIV
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article