Options for improvement of the Dutch measles vaccination schedule.
Vaccine
; 21(7-8): 721-4, 2003 Jan 30.
Article
em En
| MEDLINE
| ID: mdl-12531348
ABSTRACT
We investigated which vaccination schedule gives best protection to the vaccinating population, in case of a measles epidemic in pockets of unvaccinated individuals. We explored the effect of an additional measles vaccination (at 6 or 9 months), advancing the first measles-mumps-rubella (MMR) vaccination from 14 to 11 months, and advancing the second MMR from 9 to 4 years. Measures of protection among vaccinees (percentage of susceptibles, number of reported cases, percentage of lifetime spent susceptible) were estimated with a mathematical model of the impact of antibody level on seroconversion and immunity. Advancing the age of second MMR vaccination prevents considerably more cases among vaccinees than an extra early measles vaccination or advancing the age of first MMR vaccination.
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Base de dados:
MEDLINE
Assunto principal:
Esquemas de Imunização
/
Vacina contra Sarampo-Caxumba-Rubéola
/
Sarampo
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article