Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection.
Infect Immun
; 71(3): 1584-6, 2003 Mar.
Article
em En
| MEDLINE
| ID: mdl-12595482
ABSTRACT
Placenta-sequestered Plasmodium falciparum parasites that cause pregnancy-associated malaria (PAM) in otherwise clinically immune women express distinct variant surface antigens (VSA(PAM)) not expressed by parasites in nonpregnant individuals. We report here that parasites from the peripheral blood of clinically immune pregnant women also express VSA(PAM), making them a convenient source of VSA(PAM) expressors for PAM vaccine research.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Placenta
/
Plasmodium falciparum
/
Malária Falciparum
/
Complicações Parasitárias na Gravidez
/
Antígenos de Protozoários
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article