Hemodynamic response of the left gastric vein to glucagon in patients with portal hypertension and esophageal varices.
Ultrasound Med Biol
; 29(1): 13-7, 2003 Jan.
Article
em En
| MEDLINE
| ID: mdl-12604112
ABSTRACT
Flow direction and flow velocity of the left gastric vein (LGV) and the portal vein (PV) were examined by a Doppler sonographic machine in 33 patients with esophageal varices, before and after venous injection of glucagon (1 mg). In two patients with hepatopetal blood flow in the LGV, the flow direction changed to hepatofugal after injection of glucagon. In 31 patients with hepatofugal blood flow in the LGV, a significant increase of flow velocity was observed in the LGV in 18 patients (58.1%) and the changes (26.4 +/- 24.6%) were significantly larger than those in the PV (7.9 +/- 16.0%). The changes in flow velocity decreased in the LGV as the diameter of the LGV and the size of varices increased. In conclusion, glucagon increased collateral blood flow in the LGV in portal hypertension. However, the grade of the response decreased as the grade of portal hypertension increased.
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Base de dados:
MEDLINE
Assunto principal:
Estômago
/
Vasodilatadores
/
Glucagon
/
Varizes Esofágicas e Gástricas
/
Ultrassonografia Doppler
/
Hipertensão Portal
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article