[Progress in somatic gene therapy]. / Fremskridt i somatisk genterapi.
Ugeskr Laeger
; 165(9): 908-12, 2003 Feb 24.
Article
em Da
| MEDLINE
| ID: mdl-12661514
ABSTRACT
Therapeutic gene transfer may constitute an alternative to current treatments. Despite promising results from animal studies common use of genes as drugs awaits improved vector efficiency and easier large-scale vector production. New developments in the field include high-capacity vectors with low immunogenicity, hybrid vectors, site-specific vector integration, RNA interference, and efficient non-viral gene transfer. In this article, we review the recent progress in somatic gene therapy with focus on vector development and current examples of clinical efficiency.
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Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
/
Técnicas de Transferência de Genes
/
Vetores Genéticos
Idioma:
Da
Ano de publicação:
2003
Tipo de documento:
Article