Directional evolution of size coupled with ascertainment bias for variation in Drosophila microsatellites.
Mol Biol Evol
; 20(4): 660-2, 2003 Apr.
Article
em En
| MEDLINE
| ID: mdl-12679547
ABSTRACT
Species-specific differences in microsatellite locus length and ascertainment bias have both been proposed to explain differences in microsatellite variability and length usually observed when loci isolated in one species are used to survey variation in a related species. Here we provide a simple algebraic approach to independently estimate the contributions of true species-specific length differences and ascertainment bias. We apply this approach to a reciprocal-isolation microsatellite study and show contributions of both ascertainment bias and a true longer average microsatellite length in Drosophila melanogaster compared with D. simulans.
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Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Repetições de Microssatélites
/
Evolução Molecular
/
Drosophila
/
Modelos Genéticos
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article