Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens.
J Med Chem
; 46(10): 1795-8, 2003 May 08.
Article
em En
| MEDLINE
| ID: mdl-12723941
ABSTRACT
A series of novel 6-O-substituted homopropargyl ketolides was synthesized and evaluated against various erythromycin-resistant pathogens. Promising in vitro antibacterial activity was demonstrated for compounds bearing this structural motif.
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Base de dados:
MEDLINE
Assunto principal:
Eritromicina
/
Alcinos
/
Antibacterianos
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article