Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporine.
Transplant Proc
; 35(3 Suppl): 62S-63S, 2003 May.
Article
em En
| MEDLINE
| ID: mdl-12742469
ABSTRACT
We present the study design of a prospective, multicenter, randomized trial aimed at comparing the effects of two different combinations of sirolimus. Renal transplant recipients will be allocated to receive either sirolimus and mycophenolate mofetil (group A) or sirolimus and cyclosporine (group B). The primary endpoint will be the graft function at 3, 6, 12, 24, 36, 48, and 60 months. A number of secondary endpoints will also be considered. To obtain a significant difference in the primary endpoint 180 patients will be enrolled.
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Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Ciclosporina
/
Sirolimo
/
Sobrevivência de Enxerto
/
Ácido Micofenólico
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article