Sero-prevalence of Herpes simplex virus type 2 (HSV-2) in Rakai district, Uganda.
East Afr Med J
; 77(8): 428-30, 2000 Aug.
Article
em En
| MEDLINE
| ID: mdl-12862067
ABSTRACT
BACKGROUND:
Herpes simplex virus type 2 (HSV-2) is sexually transmitted and causes one of the genital ulcerative diseases associated with the transmission of human immunodeficiency virus type I (HIV-1).OBJECTIVE:
To determine the prevalence of serological reactivity to a type specific HSV-2 antigen (gG2) ELISA assay.SETTING:
Rakai district, Uganda.SUBJECTS:
Two hundred and one serum samples of persons aged 15-54 years. The samples were randomly selected by a computer programme.RESULTS:
Out of the 201 serum samples selected, 117 (58.2%) had serological evidence of HSV-2 infection. Twenty nine (32.2%) out of the 74 males and 88 (69.3%) out of the 127 females, respectively, had serological evidence of HSV-2 infection giving a femalemale ratio of 1.8 (95% CI 1.3-2.4). The most important risk factor for acquisition of HSV-2 in males was found to be age while in the females, the most important risk factors were age and the number of sexual partners in the previous five years.CONCLUSION:
HSV-2 was highly prevalent in this rural population of Uganda.
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Base de dados:
MEDLINE
Assunto principal:
Herpes Genital
/
Estudos Soroepidemiológicos
/
Herpesvirus Humano 2
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article