Substance P inputs to laryngeal motoneurons in the rat.
Respir Physiol Neurobiol
; 137(1): 11-8, 2003 Aug 14.
Article
em En
| MEDLINE
| ID: mdl-12871673
ABSTRACT
Substance P terminals have previously been demonstrated around retrogradely labelled posterior cricoarytenoid (PCA) motoneurons, but little is known regarding substance P inputs to other functionally identified laryngeal motoneurons. In the present study, we determined the number and distribution of close appositions between substance P immunoreactive boutons and three types of laryngeal motoneuron by using a combination of intracellular recording, dye-filling and immunocytochemistry in the rat. Cricothyroid (CT) motoneurons received 15+/-5 substance P appositions/neuron (mean+/-S.D., n = 6), PCA motoneurons received 13+/-5 (n = 6), and laryngeal constrictor (LCS) motoneurons received 11+/-4 (n = 5). In contrast to our previous finding of a preferential serotonin innervation of CT motoneurons, we found no significant difference between the substance P inputs to CT, PCA and LCS motoneurons. Our results indicate a modest role for substance P in control of laryngeal motoneuronal function.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Substância P
/
Terminações Pré-Sinápticas
/
Nervos Laríngeos
/
Neurônios Motores
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article