Antinociceptive and anti-inflammatory effects of Croton malambo bark aqueous extract.
J Ethnopharmacol
; 88(1): 11-4, 2003 Sep.
Article
em En
| MEDLINE
| ID: mdl-12902046
ABSTRACT
Croton malambo (K.) bark aqueous extract, popularly known in Venezuela as "palomatias" or "torco" was tested for acute toxicity and for its anti-inflammatory and antinociceptive effects using tail flick and writhing syndrome tests models, respectively. Croton malambo aqueous extract (6.15 mg/kg i.p.) administered intraperitoneally had a significant antinociceptive and anti-inflammatory effects compared to acetylsalicylic acid (200mg/kg p.o.) and sodium diclofenac (5.64 mg/kg p.o.). Studies to determine correlation between chemical composition and pharmacological activity are underway.
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Base de dados:
MEDLINE
Assunto principal:
Dor
/
Nociceptores
/
Extratos Vegetais
/
Anti-Inflamatórios não Esteroides
/
Analgésicos não Narcóticos
/
Croton
/
Casca de Planta
/
Fitoterapia
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article