High-dose intravenous human immunoglobulin in polymyositis resistant to treatment.
J Neurol Neurosurg Psychiatry
; 55(1): 60-2, 1992 Jan.
Article
em En
| MEDLINE
| ID: mdl-1372349
ABSTRACT
Two patients were treated with treatment-resistant polymyositis with intravenous immunoglobulin over four days at a dose of 0.4 g/kg/day. Clinical recovery followed within two months. Serum creatine kinase (CK) activity decreased to normal, and a clear improvement in muscle strength was observed. One patient showed neither clinical relapses nor increase in serum CK activity after 20 months. The other showed a mild increase in serum CK activity after 24 months and was successfully retreated with intravenous immunoglobulin. There were no significant adverse side effects.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Gama-Globulinas
/
Miosite
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article