Nitric oxide may act as a messenger between dorsal root ganglion neurones and their satellite cells.
Neurosci Lett
; 137(1): 29-32, 1992 Mar 16.
Article
em En
| MEDLINE
| ID: mdl-1378218
ABSTRACT
The distribution of NADPH-diaphorase and cyclic GMP in neonatal dorsal root ganglia in vitro has been investigated under control conditions and in response to incubation with either sodium nitroprusside or N-methyl-D-aspartate. NADPH-diaphorase activity which reveals the distribution of nitric oxide (NO) synthase in neurons was found to be intense in some dorsal root ganglion neurones and present at a lower level in the majority. Basal levels of cGMP were found to be low but when stimulated by sodium nitroprusside were found to be selectively increased in satellite cells. The results suggest that NO may function as a signalling system between neurones and satellite cells in sensory ganglia.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Neurotransmissores
/
Gânglios Espinais
/
Aminoácido Oxirredutases
/
NADPH Desidrogenase
/
Óxido Nítrico
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article