[Donath-Landsteiner hemolytic anemia. Physiopathological, diagnostic and therapeutic aspects]. / Anémie hémolytique de Donath et Landsteiner. Aspects physiopathologiques, diagnostiques et thérapeutiques.
Ann Pediatr (Paris)
; 39(9): 572-7, 1992 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-1463304
ABSTRACT
Donath-Landsteiner hemolytic anemia accounts for one third of all immunologic hemolytic syndromes in pediatric patients. Diagnosis is suggested by results of the direct Coombs test which is positive with anti-C3d, evidence of erythrophagocytosis on admission blood smears, and results of the Donath-Landsteiner test. Anti-P specificity should be routinely looked for. Management, required once the diagnosis is established, is symptomatic. Warmed red blood cell concentrates should be used for blood transfusions. Exposure to cold should be avoided. Use of maintenance corticosteroid therapy is no longer acceptable.
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Base de dados:
MEDLINE
Assunto principal:
Anemia Hemolítica Autoimune
Idioma:
Fr
Ano de publicação:
1992
Tipo de documento:
Article