Sunpollenol and five other rearranged 3,4-seco-tirucallane-type triterpenoids from sunflower pollen and their inhibitory effects on Epstein-Barr virus activation.
J Nat Prod
; 66(11): 1476-9, 2003 Nov.
Article
em En
| MEDLINE
| ID: mdl-14640522
ABSTRACT
Six new rearranged 3,4-seco-tirucallane-type triterpenoids (1-6) have been isolated from the diethyl ether extract of the pollen grains of sunflower (Helianthus annuus). These compounds were evaluated with respect to their inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) in Raji cells. All of the compounds tested showed potent inhibitory effects on EBV-EA activation (97-100% inhibition at 1 x 10(3) mol ratio/TPA).
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Pólen
/
Triterpenos
/
Helianthus
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article