Hormone use and cognitive performance in women of advanced age.
J Am Geriatr Soc
; 52(2): 182-6, 2004 Feb.
Article
em En
| MEDLINE
| ID: mdl-14728625
ABSTRACT
OBJECTIVES:
To explore the association between hormone replacement therapy (HRT) and cognitive performance in a group of elderly women (>/=75) using a battery of well-standardized neuropsychological instruments.DESIGN:
Equivalent samples from existing cohort.SETTING:
Healthcare provider organization.PARTICIPANTS:
All women enrolled were participants in an ongoing study of the association between HRT and the prevalence and incidence of dementia. Prescription records were used to establish HRT status. Fifty-eight users and 47 nonusers of HRT participated in this substudy. MEASUREMENTS Given previous reports that HRT has a positive effect on verbal memory, the California Verbal Learning Test and the Logical Memory Test were used as primary outcomes. A range of validated tests that assess other cognitive domains was also included.RESULTS:
There were no significant differences between users and nonusers of HRT on any cognitive measures.CONCLUSION:
Given equivalent groups of users and nonusers of HRT no support was found for the hypothesis that use of HRT improves cognitive performance in older women.
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Base de dados:
MEDLINE
Assunto principal:
Terapia de Reposição de Estrogênios
/
Cognição
/
Estrogênios
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article