Adrenal suppression and failure to thrive after steroid injections for periocular hemangioma.
Ophthalmology
; 111(2): 389-95, 2004 Feb.
Article
em En
| MEDLINE
| ID: mdl-15019396
ABSTRACT
PURPOSE:
To evaluate the effects of steroid injections for periocular capillary hemangioma on adrenal function and body composition.DESIGN:
Noncomparative, interventional case series.PARTICIPANTS:
Four patients with periocular hemangioma.METHODS:
Four white female infants with sight-threatening periocular hemangiomata received a combination of steroid injections of triamcinolone and betamethasone. In the first 2 cases, injections were perilesional and in the other 2, intralesional. MAIN OUTCOMEMEASURES:
The infants were monitored by serial measurements of basal serum cortisol concentrations, responses to the Synacthen stimulation test, measurement of growth and of weight gain, and, in one case, more detailed anthropometric measures of body composition.RESULTS:
Prolonged suppression of circulating serum cortisol concentrations and cortisol responses to the Synacthen stimulation test were noted in 3 cases, and marked failure to thrive was noted in all 4 cases.CONCLUSIONS:
Adrenal suppression after steroid injection for periocular capillary hemangioma is a potentially life-threatening complication. Failure to thrive is also a frequent side effect of treatment. Ophthalmologists should undertake the above treatment in consultation with a pediatric endocrinologist.
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Base de dados:
MEDLINE
Assunto principal:
Insuficiência Adrenal
/
Hemangioma Capilar
/
Neoplasias Palpebrais
/
Insuficiência de Crescimento
/
Glucocorticoides
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article