Threonine is the best substrate for D-lactate formation in octopus tentacle.
Amino Acids
; 26(2): 169-74, 2004 Mar.
Article
em En
| MEDLINE
| ID: mdl-15042447
ABSTRACT
Carbon sources for D-lactate and enzyme activities related to D-lactate formation were investigated using cell-free homogenates of Octopus vulgaris tentacle tissue. The results are as follows a) The best precursor for D-lactate formation was threonine and second best precursors were glycine and fructose-1,6-bisphosphate. Threonine and glycine served as precursors only in presence of glutathione. b) Both amino acids were precursors for methylglyoxal from which D-lactate was synthesized. Alanine, cysteine and serine were not precursors. We present a metabolic map for D-lactate formation in octopus in order to explain these experimental results.
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Base de dados:
MEDLINE
Assunto principal:
Treonina
/
Ácido Láctico
/
Extremidades
/
Octopodiformes
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article