Nicotine replacement therapy-associated syndrome of inappropriate antidiuretic hormone.
South Med J
; 97(3): 322-4, 2004 Mar.
Article
em En
| MEDLINE
| ID: mdl-15043349
ABSTRACT
Nicotine has been documented to regulate the release of plasma arginine vasopressin (AVP). The literature is inconclusive about the effects of nicotine replacement therapy on AVP release, although cigarette smoking has been shown to increase the release of AVP. No clinical case reports have documented the possible association between nicotine replacement and hyponatremia through AVP release. We report a case of a 39-year-old man who experienced syndrome of inappropriate antidiuretic hormone while on nicotine patch therapy. We theorize that the constant serum concentration of nicotine levels provided through the patch may cause hyponatremia through the continuous stimulation of vasopressin.
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Base de dados:
MEDLINE
Assunto principal:
Síndrome de Secreção Inadequada de HAD
/
Nicotina
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article