Oligodendrocyte precursors on the move: mechanisms directing migration.

ABSTRACT

Oligodendrocyte precursor cells traverse long distances to reach their axonal targets. The molecules that influence their migration include a combination of short-range attractants and repellents and long-range chemoattractants and chemorepellents. Here, the authors review mechanisms that direct oligodendrocyte precursor cells as they migrate throughout the developing CNS.