One-year health assessment of adult survivors of Bacillus anthracis infection.
JAMA
; 291(16): 1994-8, 2004 Apr 28.
Article
em En
| MEDLINE
| ID: mdl-15113818
ABSTRACT
CONTEXT Little is known about potential long-term health effects of bioterrorism-related Bacillus anthracis infection. OBJECTIVE:
To describe the relationship between anthrax infection and persistent somatic symptoms among adults surviving bioterrorism-related anthrax disease approximately 1 year after illness onset in 2001. DESIGN, SETTING, ANDPARTICIPANTS:
Cross-sectional study of 15 of 16 adult survivors from September through December 2002 using a clinical interview, a medical review-of-system questionnaire, 2 standardized self-administered questionnaires, and a review of available medical records. MAIN OUTCOMEMEASURES:
Health complaints summarized by the body system affected and by symptom categories; psychological distress measured by the Revised 90-Item Symptom Checklist; and health-related quality-of-life indices by the Medical Outcomes Study 36-Item Short-Form Health Survey (version 2).RESULTS:
The anthrax survivors reported symptoms affecting multiple body systems, significantly greater overall psychological distress (P<.001), and significantly reduced health-related quality-of-life indices compared with US referent populations. Eight survivors (53%) had not returned to work since their infection. Comparing disease manifestations, inhalational survivors reported significantly lower overall physical health than cutaneous survivors (mean scores, 30 vs 41; P =.02). Available medical records could not explain the persisting health complaints.CONCLUSION:
The anthrax survivors continued to report significant health problems and poor life adjustment 1 year after onset of bioterrorism-related anthrax disease.
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Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Sobreviventes
/
Bioterrorismo
/
Antraz
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article