Isolated extramedullary relapse of acute myelogenous leukemia as a uterine granulocytic sarcoma in an allogeneic hematopoietic stem cell transplantation recipient.
Yonsei Med J
; 45(2): 330-3, 2004 Apr 30.
Article
em En
| MEDLINE
| ID: mdl-15119007
ABSTRACT
We report an unusual case of acute myelogenous leukemia in a patient who showed an extramedullary relapse in her uterus, without bone marrow recurrence, two years after an allogeneic bone marrow transplant. She complained of irregular vaginal spotting, and magnetic resonance imaging demonstrated a uterine mass. A biopsy revealed a massive infiltration of immature myeloid cells. A variable number of tandem repeats (VNTR) based on an examination of peripheral blood cells showed full donor chimerism. After receiving chemotherapy, her uterine mass had completely resolved. She has remained in complete remission for more than 6 months. This case suggests that physicians should be aware of the possibility of a uterine relapse in female bone marrow transplant recipients with acute myelogenous leukemia.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uterinas
/
Leucemia Mieloide Aguda
/
Transplante de Células-Tronco Hematopoéticas
/
Sarcoma Mieloide
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article