Evaluating the safety of food and color additives with pharmacokinetic data.
Crit Rev Food Sci Nutr
; 32(2): 191-5, 1992.
Article
em En
| MEDLINE
| ID: mdl-1515047
ABSTRACT
Pharmacokinetic studies are designed to quantify, as a function of time, the processes associated with absorption, distribution, metabolism, and excretion of a chemical in experimental animals or in humans. Such studies have played an important role in drug safety evaluation and could be very useful in the safety evaluation of food and color additives. This presentation provides an overview of the potential use of metabolic and pharmacokinetic data in the design and evaluation of toxicological studies and in the assessment of the potential hazard to humans from exposure to food or color additives.
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Base de dados:
MEDLINE
Assunto principal:
Aditivos Alimentares
/
Corantes de Alimentos
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article