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Immunoenhancement to prevent nosocomial coagulase-negative staphylococcal sepsis in very low-birth-weight infants.
Devlin, Lori A; Lassiter, Herbert A.
Afiliação
  • Devlin LA; Division of Neonatal Medicine, Department of Pediatrics, University of Louisville School of Medicine, 571 S. Floyd St., Suite 300, Louisville, KY 40202-3830, USA.
Clin Perinatol ; 31(1): 69-75, 2004 Mar.
Article em En | MEDLINE | ID: mdl-15183657
Extremely low-birth-weight infants are susceptible to invasion by coagulase-negative staphylococci (CONS). This article reviews the epidemiology, immunology, and microbiology of CONS and describes recent clinical trials of immunoenhancing agents such as intravenous immunoglobulin, granulocyte colony-stimulating factor, granulocyte macrophage colony-stimulating factor, and mouse humanized chimeric anti-lipoteichoic acid antibody. Potential avenues of research to reduce the incidence of nosocomial CONS sepsis in premature neonates are presented.
Assuntos
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Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Staphylococcus / Recém-Nascido de Baixo Peso / Adjuvantes Imunológicos / Infecção Hospitalar / Coagulase Idioma: En Ano de publicação: 2004 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Staphylococcus / Recém-Nascido de Baixo Peso / Adjuvantes Imunológicos / Infecção Hospitalar / Coagulase Idioma: En Ano de publicação: 2004 Tipo de documento: Article