At the crossroads of growth control; making ribosomal RNA.
Curr Opin Genet Dev
; 14(2): 210-7, 2004 Apr.
Article
em En
| MEDLINE
| ID: mdl-15196469
ABSTRACT
Although the mechanisms of cell cycle control are well established, the factors controlling cell growth and target size are still poorly understood. Much evidence suggests that ribosome biogenesis, and in particular the synthesis of the rRNAs, plays a central role not only in permitting growth, but also in regulating it. In the past few years we have begun to penetrate the network linking rRNA gene transcription to growth.
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Base de dados:
MEDLINE
Assunto principal:
RNA Ribossômico
/
Crescimento
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article