Modulative influence of lysozyme dimer on defence mechanisms in the carp (Cyprinus carpio) and European sheatfish (Silurus glanis) after suppression induced by herbicide Roundup.
Pol J Vet Sci
; 7(2): 123-8, 2004.
Article
em En
| MEDLINE
| ID: mdl-15230544
ABSTRACT
Immunomodulation is a commonly used method of prophylaxis in humans and animals. Lysozyme dimer (KLP-602) was used at a dose of 50 ug/kg b.w. in order to correct the immunosuppression caused by the action of herbicide glyphosate (Roundup- Monsanto), which was used in a single bath for 10 minutes in a concentration of 100 mg/l of water. The investigations were carried out on 2 species of fish the carp (Cyprinus carpio L.) and european catfish (Silurus glanis L.). Herbicide glyphosate caused a decrease in metabolic and phagocytic activity (RBA and PKA) and in proliferative response stimulated by Con A and LPS in carp and european catfish. The immunosuppression sustained for about 2 weeks. The results obtained indicate the possibility of correction of immunosuppression applying lysozyme dimmer (KLP-602) after use of which, the level of the studied indexes increased.
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Base de dados:
MEDLINE
Assunto principal:
Peixes-Gato
/
Carpas
/
Muramidase
/
Adjuvantes Imunológicos
/
Sistema Imunitário
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article