Characterization of a novel selenium methyltransferase from freshwater bacteria showing strong similarities with the calicheamicin methyltransferase.
Biochim Biophys Acta
; 1679(1): 80-5, 2004 Jul 13.
Article
em En
| MEDLINE
| ID: mdl-15245920
ABSTRACT
A novel group of Se-methyltransferases is presented. The genetic determinant, named mmtA, which revealed this group was isolated from selenite and selenate-resistant freshwater bacteria. E. coli expressing mmtA and grown with a Se supplement emitted dimethyl selenide (DMSe) and dimethyl diselenide (DMDSe). Phylogenetic analysis divided MmtA-like bacterial sequences into two clusters, one grouping MmtA with S- and O-methyltransferases, and one grouping UbiE C-methyltransferases. Se methylation by some of these MmtA phyletic neighbours was investigated.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Metiltransferases
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article