[Analysis of anti-microbial resistance of Escherichia coli that caused infection in urogenital system].
Di Yi Jun Yi Da Xue Xue Bao
; 24(8): 940-2, 945, 2004 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-15321769
ABSTRACT
OBJECTIVE:
To study the anti-microbial resistance of Escherichia coli (E.coli) that caused infection in urogenital system.METHOD:
Anti-microbial susceptibility tests for 148 strains of E.coli were conducted by disc diffusion technique.RESULTS:
In 28 commonly used antibiotics, the resistance rates of E. coli to beta-lactam and quinolones were high (73.6%-86.4%). High resistance rates to the first- and the second-generation cephalosporin (cefradime, cephazolin and cefaclor) were also observed (44%). Resistance rate to ceftazidime is the lowest (10.1%) in the third-generation cephalosporin. The resistance rates of E. coli to piperacillin, pefoperazone and ampicillin were 84.5%, 44.6% and 83.0% respectively. Combined antibiotic and beta-lactam inhibitor gave lower resistance rates than antibiotic alone (piperacillin/tazobactam, cefoporazone/sulbactam and ampicillin/sulbactam were 4.1%, 10.8% and 52.0% respectively, P<0.01). Of 148 E. coli isolates, 38 strains were capable of yielding extended-spectrum beta-lactamases (ESBLs) (25.7%), 110 strains were not able to produce ESBLs (74.3%) and the resistance rates of isolates with ESBLs to 28 antibiotics were significantly lower than those of isolates without ESBLs.CONCLUSION:
Antibiotic/beta-lactam inhibitor and nitrofurantoin are effective for urogenital infections caused by E. coli.
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Base de dados:
MEDLINE
Assunto principal:
Infecções Urinárias
/
Resistência beta-Lactâmica
/
Farmacorresistência Bacteriana
/
Escherichia coli
/
Infecções por Escherichia coli
Idioma:
Zh
Ano de publicação:
2004
Tipo de documento:
Article