Evaluation of dynamic studies of MR mammography for the diagnosis of intraductal lesions with nipple discharge.
Breast Cancer
; 11(3): 288-94, 2004.
Article
em En
| MEDLINE
| ID: mdl-15550848
ABSTRACT
OBJECTIVES:
We assessed the utility of dynamic magnetic resonance imaging (MRI) in differentiating benign from malignant lesions of the breast and then applied MRI to diagnose intraductal breast tumors with nipple discharge.METHODS:
Gadolinium (Gd)-enhanced MR mammography was performed on 74 patients with breast tumors and 8 patients with nipple discharge.RESULTS:
The steepest slopes of the contrast medium uptake (S slope) s from time-intensity curves were significantly different between malignant and benign lesions. At S slope threshold of 0.95% /second, malignancy was predicted with a sensitivity and specificity of 75% . Six of 8 cases with nipple discharge were successfully identified by MR ductography by injecting Gd-DTPA into discharging ducts. Among them, 2 non-invasive ductal carcinomas were differentiated from benign lesions by the S slope value.CONCLUSIONS:
Dynamic MR mammography is an useful modality for differentiating breast lesions and has potential for evaluating intraductal lesions with nipple discharge.
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Base de dados:
MEDLINE
Assunto principal:
Mama
/
Neoplasias da Mama
/
Mamografia
/
Carcinoma Intraductal não Infiltrante
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article