Malignant lymphoma in ferrets: clinical and pathological findings in 19 cases.
J Comp Pathol
; 106(1): 37-47, 1992 Jan.
Article
em En
| MEDLINE
| ID: mdl-1556256
ABSTRACT
The clinical and pathological findings in 19 ferrets (Mustela putorius furo) with malignant lymphoma are reviewed. Peripubescent ferrets had rapidly progressive stage IV high grade immunoblastic or small non-cleaved cell lymphoma. Adult ferrets had stage II or IV low grade diffuse small lymphocytic (DSL) lymphoma, stage IV high grade small non-cleaved cell lymphoma, or stage IV high grade immunoblastic polymorphous (IBP) lymphoma. Three ferrets had concurrent IBP and DSL lymphoma involving different organs. The IBP admixture of immunoblasts, large atypical lymphocytes, Reed-Sternberg-like cells, lymphoblasts and small lymphocytes has been associated with certain retrovirally associated lymphomas and nodal hyperplasias in man, non-human primates and cats. Aleutian disease, a parvovirus-induced lymphoproliferative disease, also involves clinical and histological features similar to certain lymphomas in ferrets. Seven ferrets tested were seronegative for feline leukaemia virus antigen. Only one of eight ferrets was positive for Aleutian parvovirus antibody. The clinical and pathological findings are suggestive of a viral aetiology for certain lymphomas in ferrets.
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Base de dados:
MEDLINE
Assunto principal:
Leucemia Linfocítica Crônica de Células B
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Furões
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article