[Cisplatin and derivatives with radiation therapy: for what clinical use?]. / Sels de platine et radiothérapie: vingt ans de pratique.
Cancer Radiother
; 8 Suppl 1: S88-94, 2004 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-15679253
ABSTRACT
Since its discovery by Rosenberg in 1965, cisplatin and its derivatives have appeared as the most important chemotherapeutic agents, particularly for their radiosensitizing properties and their clinical use with radiation. In spite of numerous preclinical and clinical studies, optimal schedules of platin and radiotherapy combination have to be defined. The first part of this overview will describe biological mechanisms of interaction between radiation therapy and platinum derivatives. The second part will report the major clinical impact of their association.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organoplatínicos
/
Radiossensibilizantes
/
Carboplatina
/
Cisplatino
/
Neoplasias
Idioma:
Fr
Ano de publicação:
2004
Tipo de documento:
Article