Pachyelasides A-D, novel molluscicidal triterpene saponins from Pachyelasma tessmannii.
J Agric Food Chem
; 53(3): 608-13, 2005 Feb 09.
Article
em En
| MEDLINE
| ID: mdl-15686409
ABSTRACT
This is the first report for secondary metabolites in an African medicinal plant, Pachyelasma tessmannii (Leguminosae). Four novel saponins, pachyelasides A-D, were isolated from the methanol extract of the root bark by using recycling HPLC. These compounds showed molluscicidal activity (LD(50) < or =8.0 mug/mL) against the South American snail, Biomphalaria glabratus. The structures were determined on the basis of extensive nuclear magnetic resonance spectroscopic and matrix-assisted laser desorption/ionization time-of-flight mass spectrometric studies.
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Base de dados:
MEDLINE
Assunto principal:
Saponinas
/
Triterpenos
/
Biomphalaria
/
Fabaceae
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article