Stage migration influences on stage-specific survival comparison between D1 and D3 gastric cancer surgeries.
Eur J Surg Oncol
; 31(2): 153-7, 2005 Mar.
Article
em En
| MEDLINE
| ID: mdl-15698731
ABSTRACT
AIMS:
We evaluate the influency stage migration in a randomised trial comparing D1 (N 1 lymphadenectomy) and D3 (N 1, 2 and 3 lymphadenectomy) dissections.METHODS:
Two hundred and thirteen curatively resected patients were analysed, with this TNM data.RESULTS:
After applying D3 patients' data according to simulated D1 staging, D3 resections were associated with up-staging to N2-3 levels in 8% of patients according to the N stage. The likelihood of N-status migration increased with increasing depth of invasion into the gastric wall. The increases in the calculated survival rate after stage migration on known 5-year survival rates were 2% in stage IB, 1% in stage II, 4% in stage IIIA, and 1% in stage IIIB.CONCLUSIONS:
Stage migration secondary to meticulous lymph node dissection affects stage-specific survival rates. True therapeutic survival benefit of D3 resection can only be assessed in this context.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Gastrectomia
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article