Structure-based design of protein tyrosine phosphatase-1B inhibitors.
Bioorg Med Chem Lett
; 15(10): 2503-7, 2005 May 16.
Article
em En
| MEDLINE
| ID: mdl-15863305
ABSTRACT
Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.
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Base de dados:
MEDLINE
Assunto principal:
Tiadiazinas
/
Proteínas Tirosina Fosfatases
/
Inibidores Enzimáticos
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article